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Journal : Indonesian Journal of Pharmaceutical Education

Analisis Manajemen Pengelolaan Logistik Sediaan Farmasi dan Perbekalan Kesehatan di Instalasi Farmasi Widy Susanti Abdulkadir; Madania Madania; Teti S. Tuloli; Nur Rasdianah; Juliyanty Akuba
Indonesian Journal of Pharmaceutical Education Vol 2, No 1 (2022): Januari-April 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i1.11399

Abstract

Drug management is a set of optimally conducted activities related to the aspects of drug planning, procurement, storing, distribution, and extermination. This was done to achieve the proper drug amount, types, supply, maintenance, and medication. Earlier observstion revealed problems in managing pharmaceutical stock and consumables, where some of the stocks are empty. This qualitative descriptive research focus on identifying pharmaceutical logistic stock and health supplies comprising drug planning, procurement, storing, distribution, and extermination in the pharmaceutical unit of Gorontalo. The primary data were obtained from questionnaires based on technical guidance by the health ministry while the secondary were obtained from related documents. Based on the findings, the pharmaceutical stock planning and storing process at the pharmacy unit did not meet the health ministry standards, which is opposite to the procurement, distribution, and extermination process.
Analisis Biaya dan Nilai Utilitas pada Pasien Hemodialisis yang Diberikan Terapi Erythropoiesis di Rumah Sakit Madania Madania; Tety Sutriyati Tuloli; Nur Rasdianah; Juliyanty Akuba
Indonesian Journal of Pharmaceutical Education Vol 1, No 3 (2021): September-Desember 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i3.11360

Abstract

Chronic kidney failure is a condition where there is a gradual decline in kidney function. Chronic kidney disease is often followed by complications of anemia. The use of erythropoietin therapy in chronic renal failure patients undergoing hemodialysis requires no small amount of money. This affects the quality of life (utility). The purpose of this study is to measure costs and utility values using the EQ-5D-5L (EuroQol-Five Dimensions) instrument, VAS (Visual Analog Scale), and costs based on the patient's perspective at Prof.Aloei Saboe Hospital. This study is a prospective cross-sectional approach. Data was collected using the EQ-5D-5L and EQ-VAS questionnaires. The subjects of the study were hemodialysis patients as many as 45 met the inclusion criteria. The results showed that the most widely used Erythropoietin therapy was single Hemapo. The results of the calculation of the estimated cost of each hemodialysis patient from the perspective of a patient for one month of therapy are Rp. 7,112,000. The average expenditure of patient transportation costs is Rp. 50,111. The average cost of food for the patient is Rp. 25,000.Utility value based on average Indonesian set value 0.673 (sufficiently feeling well)and VAS score 71.4 (health status is quite healthy).
Interaksi Obat Pada Pasien Diabetes Melitus Tipe 2 Dengan Penyakit Penyerta Di Rumah Sakit Otanaha Kota Gorontalo Nur Rasdianah; Faramita Hiola; A. Mu’thi Andy Suryadi; Athira Sri Wahyuni Gani
Indonesian Journal of Pharmaceutical Education Vol 1, No 1 (2021): Januari-April 2021
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v1i1.9953

Abstract

As the numbers of cases continue to soar, diabetes mellitus or DM is one the most common disease in Indonesia. The WHO predicts that in 2030, numbers of diabetics in Indonesia will rise up to 21.3 million people, compared to 8.4 million people in 2000. Regarding the treatment, most of diabetes cases are commonly treated with pharmacological therapy. In this regard, polypharmacy and medications-related problems might occur during the treatment to control blood glucose level that is concurrent with the treatment of other diseases. Drug Interaction is a common medication-related problem. The present study is aimed to investigate the cases of drug interaction in patients with type-2 DM with comorbid diseases during the period of January-December 2019 in Otanaha Hospital, Gorontalo. As based on the inclusion criteria, the study involved 92 patients with type-2 DM and comorbid disease involved combination of metformin-glimepiride (47%), insulin (19%), metformin (14%), and glimepiride (9%). Moreover, based on the observation, minor interaction occurred the most (47%), followed by moderat interaction (31%) and major interaction. To sum up, the cases of drug interaction in patients with type-2 DM and comorbid disease in Otanaha Hospital, Gorontalo are relatively high. It is further concluded that the pharmacist’s role is influential to supervise and monitor the patients medication intake.
Gambaran Penggunaan Obat Off-Label Pada Pasien Pediatrik Rawat Inap di Rumah Sakit Teti Sutriati Tuloli; Nur Rasdianah; Andi Makkulawu; Dizky Ramadani Putri Papeo; Maimun Datau
Indonesian Journal of Pharmaceutical Education Vol 2, No 2 (2022): Mei-Agustus 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.11449

Abstract

Off-label drugs can be interpreted as drugs that are used not in accordance with drug information, distribution permits and sales licenses from the Marketing Authorization (MA) related to indications, age, dosage, route of administration and contraindications. The use of off-label drugs in children occurs because of incomplete data on pharmacokinetics, pharmacodynamics and side effect of a drug. It is because clinical research in children is quite difficult and not in accordance with research ethics and morals, so it has the potential to cause errors in treatment and unwanted drug reactions. This study aims to describe the use of off-label drugs in hospitalized pediatric patients at RSUD of Dr. M.M Dunda Limboto, Gorontalo District, Gorontalo Province. This is an  observational study using cross sectional design and retrospective data collection. The sampling technique applies a purposive sampling technique with a total of 155 patients who meet the inclusion criteria during the January-June 2020 period. The finding shows that from 155 patient medical records, there are 172 (16,51%) off-label drug used with a total of 1042 drugs. The off-label drugs used in the indication category are 64,53%, the off-label drugs used in dose category are 17,44%, the off-label drugs used in age category are 14,53%, the off-label drugs used in route of administration category are 3,49% and the off-label drugs used in contraindications category are not found. The are the most off-label drugs used in each category, including domperidone (off-label in indications and dose), rhinofed (off-label in age) and salbutamol (off-label in route of administration).
Gambaran Interaksi Obat Pada Pasien Gagal Ginjal Kronik Dalam Proses Hemodialisis Siti Alfanda Makmur; Madania Madania; Nur Rasdianah
Indonesian Journal of Pharmaceutical Education Vol 2, No 3 (2022): September-Desember 2022
Publisher : Jurusan Farmasi Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/ijpe.v2i2.13333

Abstract

Chronic Kidney Disease (CKD) is a condition in which there is a decrease in kidney function due to the presence of chronic and irreversible renal parenchyma. Patients with chronic disease often require a combination of several drugs. The administration of drugs combination is generally expected to have a beneficial effect. However, in some cases, drug interactions resulted in ineffective treatment and the emergence of unexpected events. This research aimed to determine drug interactions in patients with chronic kidney disease who are undergoing hemodialysis in the Inpatient Installation of Dr. M.M Dunda Limboto Hospital. This research was observational using a cross-sectional design and retrospective data collection. The sampling technique used was a purposive sampling technique with a total of 51 patient who met the inclusion criteria during the July-Desember 2020 period. Drug interaction data analysis was based on the Drug Interaction Checker and Drug Interaction Facts. The results showed that the most widely used drugs in patients with chronic kidney disease at Dr. M.M Dunda Limboto Hospital were anti-hypertensi drugs (17%), vitamins and minerals (13.30%), and gastrointestinal (11.32%). Drugs interactions with pharmacodynamic mechanisms were 31 cases (53.45%), pharmacokinetics were 21 cases (36.21%), and 6 cases were unknown (10.34%). The level of clinical significance in patients with chronic kidney disease was 75.86% moderate, 13.80% minor, and 10.34% major.